Nz dermnet - Tofacitinib (Xeljanz, Xeljanz XR ®, US) is an oral small- molecule inhibitor of Janus kinase (JAK) 1 and 3 that is used to treat psoriatic arthritis, rheumatoid arthriti s, inflammatory bowel disease, and ankylosing spondylitis. JAK enzymes respond to extracellular growth factors, and cytokines which activate signal transduction and cell ...

 
Nz dermnetNz dermnet - Angioedema is caused by an increase in local capillary permeability and plasma extravasation, usually mediated by mast cells, histamine, or bradykinin release. Angioedema is most commonly histamine-mediated; mast cell and basophil stimulation results in histamine release. Angioedema with urticaria tends to suggest a histaminergic …

Dermatosis is a generic term for a disease of the skin. When examining the skin, a dermatologist assesses distribution, morphology and arrangement of skin lesions: their … Scabies is a transmissible skin disease caused by the ectoparasitic mite Sarcoptes scabiei var. hominis. This variant infests humans only; scabies cannot be caught or transferred to other animals. Scabies is a highly contagious infestation of the human epidermis. Scabies was described by Aristotle who likened the disease to lice of the flesh. Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss.A skin tag is a common soft harmless lesion that appears to hang off the skin. It is also described as: Skin tags develop in both men and women as they grow older. They are skin coloured or darker and range in size from 1mm to 5cm. They are most often found in the skin folds (neck, armpits, groin). They tend to be more numerous in obese persons ... Introduction. Itch is defined by a desire to scratch. An acute or chronic itchy rash is most often due to dermatitis / eczema. Dermatitis can be primary, or secondary to scratching. Stages include: Acute dermatitis: red, oozy, swollen skin. Subacute dermatitis: red, dry skin. Chronic dermatitis: skin coloured or dark, dry, thickened skin with ... DermNet does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.Aphthous ulceration is classified into three types. Recurrent minor aphthous ulcer (80%). This is less than 5 mm in diameter and heals within 1–2 weeks. Major aphthous ulcer, which is large (often more than 10 mm) and takes weeks or months to heal and leaves a scar. Herpetiform ulcers, which are multiple pinpoint ulcers that heal within a month. With crawling, the extensor aspects of the elbows and wrists, knees and ankles are affected. The distribution becomes flexural with walking, particularly involving the antecubital and popliteal fossae (elbow and knee creases). Dribble and food can cause dermatitis around the mouth and chin. Carotenoderma is due to carotenaemia. Primary carotenaemia is usually due to excessive intake of carotenoid-containing foods or supplements. Carotene is found in all pigmented fruits and vegetables. High levels are associated with a deep yellow, orange, or green colour. Examples of fruit and vegetables with a high β-carotene content include ...Scalp psoriasis is a skin condition characterised by red, thickened, well- demarcated patches or plaques with overlying silvery-white scales, affecting part or all of the scalp. It can be contained within the hairline, though frequently affects the back of the head, or extends onto the forehead ( facial psoriasis ), ears, or neck.What are the clinical features of guttate psoriasis? Acute onset over days. Numerous small patches (<1 cm) Pink, scaly, thin patches or plaques of psoriasis. Scale can be subtle in early lesions. Widespread lesions predominantly over the trunk and limbs. Lesions on the face, scalp, and ears tend to be faint and short-lived. Introduction. If you don't find what you are looking for on this page, try DermNet's Glossary of Dermatology Terms or Dermatological diagnoses often have more than one name. . DermNet refers to various resources when naming conditions, including the World Health Organisation (WHO)'s International Classification of Diseases (see ICD11 coding tool), and the Systematized Nomenclature of Medicine ... Pityriasis rosea is a self-limiting rash that resolves in about 6–10 weeks. It is characterised by a large circular or oval "herald patch" on the chest, abdomen, or back, followed by …Angioedema is caused by an increase in local capillary permeability and plasma extravasation, usually mediated by mast cells, histamine, or bradykinin release. Angioedema is most commonly histamine-mediated; mast cell and basophil stimulation results in histamine release. Angioedema with urticaria tends to suggest a histaminergic …DermNet NZ revision August 2021. Table of contents. Introduction Demographics Causes Clinical features Diagnosis Treatment Outlook. What is pityriasis versicolor? Pityriasis …Skin conditions caused or aggravated by infection by malassezia include: Pityriasis versicolor – most often due to M. globosa, M. sympodialis and M. furfur. Malassezia folliculitis due to the yeast growing in the hair follicles where they produce inflammation. Steroid acne. Seborrhoeic dermatitis, dandruff, sebopsoriasis and facial or scalp ... Basal cell naevus syndrome is a rare genetic cancer syndrome characterised by multiple early onset basal cell carcinomas, odontogenic keratocysts and other tumours, and other abnormalities. Basal cell naevus syndrome (BCNS) is probably best known as Gorlin syndrome, and is also called naevoid basal cell carcinoma syndrome, amongst many other names. Acne conglobata is a rare severe form of nodulocystic acne. It presents with groups of multiple comedones and inflammatory papules, pustules, and nodules involving the trunk, limbs, and buttocks. Interconnecting abscesses and draining sinuses become secondarily infected causing pain and malodour. Healing is slow, leaving unsightly hypertrophic ...What is cellulitis? Cellulitis is a common bacterial skin infection of the lower dermis and subcutaneous tissue. It results in a localised area of red, painful, swollen skin, and systemic symptoms. Left untreated, cellulitis can be life-threatening. Similar symptoms are experienced with the more superficial infection, erysipelas, so cellulitis and erysipelas …Scalp psoriasis is a skin condition characterised by red, thickened, well- demarcated patches or plaques with overlying silvery-white scales, affecting part or all of the scalp. It can be contained within the hairline, though frequently affects the back of the head, or extends onto the forehead ( facial psoriasis ), ears, or neck.Hereditary haemorrhagic telangiectasia (HHT) is also known as Osler-Rendu-Weber syndrome. It is a rare inherited disorder that affects blood vessels throughout the body and is characterised by a tendency for bleeding ( haemorrhage, American spelling ‘hemorrhage’), in particular recurrent epistaxis (nosebleeds); and skin telangiectasia … Sun damage ( photoageing, actinic keratoses) Repeated prior episodes of sunburn. Fair skin, blue eyes and blond or red hair — note; BCC can also affect darker skin types. Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, sebaceous naevus) Inherited syndromes: BCC is a particular problem for families with basal cell naevus ... Malassezia folliculitis, also known as pityrosporum folliculitis, is an infection of the pilosebaceous unit caused by lipophilic Malassezia yeasts particularly M. globosa, M. sympodialis and M. restricta. Malassezia yeast are normal inhabitants of the human skin surface and only cause disease under specific conditions.Dumping syndrome is the association of facial flushing with racing heart, sweating, dizziness, weakness, and tummy upset. Symptoms begin after gastric surgery and are provoked after a meal or ingestion of hot drinks or strong glucose. The syndrome becomes worse after the menopause.Lichen planus is a chronic inflammatory condition affecting the skin and mucosal surfaces. Learn about its symptoms, causes, diagnosis, treatment, and complications with images …DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. Learn … Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss. Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. It is also known as polymorphous light eruption, sun allergy, sun poisoning, prurigo aestivalis, summer eruption/prurigo, or eczema solare. Juvenile spring eruption is a variant of PMLE.There are many types of drug eruption, which range from a clinically mild and unnoticed rash to a severe cutaneous adverse reaction (SCAR) that may be life-threatening. The most common drug eruptions are: Morbilliform or exanthematous drug eruption. Urticaria and/or angioedema (which rarely leads to anaphylaxis ). SCARs are rare:Periorificial dermatitis (POD) is a chronic inflammatory skin eruption around the eyes, nostrils, mouth, and genitals. It may be limited to a single orifice or involve multiple … DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. We have information about almost every skin condition and have a library of over 20,000 dermatology images. All of our content is created or reviewed by a dermatologist and we ... Risankizumab is an interleukin IL-23 antagonist indicated for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy [1]. Risankizumab was approved by the US Food and Drug Administration (FDA) in April 2019, in Japan in March 2019, and by the European Union in March 2019.Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss.Authoritative facts about the skin from DermNet New Zealand. DermNet provides Google Translate, a free machine translation service. Note that this may not provide an exact translation in all languages. Topics A-Z. Images. Cases. Jobs. AI dataset. More . Skin checker; About; Browse ... The Australian and New Zealand Melanoma …Dermatitis herpetiformis (DH) is an inflammatoryimmunobullous disease of the skin and a cutaneousmanifestation of coeliac (celiac) disease, a gluten-sensitive enteropathy. The name herpetiformis is derived from the tendency for blisters to appear in clusters, resembling herpes simplex. However, DH is not due to viral infection.Moisturisers are products used to add moisture to the skin. Emollients are products used to soften and smooth skin (eg, lanolin, glycerol stearate). Although the terms emollient and moisturiser are often used synonymously, emollients can also be described as a specific ingredient of moisturisers. There are often a number of available moisturisers.Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss.Definition. Dermatology is the medical discipline that is concerned with the diagnosis and treatment of diseases of the skin, hair, and nails in both children and adults. Specialists in dermatology are called dermatologists.. The New Zealand Dermatological Society’s definition is comprehensive: “Dermatology involves but is not limited to study, research, …Polymorphic light eruption (PMLE) is a seasonal, acquired, idiopathic photodermatosis occurring in spring and early summer. It is also known as polymorphous light eruption, sun allergy, sun poisoning, prurigo aestivalis, summer eruption/prurigo, or eczema solare. Juvenile spring eruption is a variant of PMLE.A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index. Completing a PASI score takes a few minutes and experience to calculate it accurately. Link to DermNet's patient-oriented PASI score tool (PO-PASI) if you have psoriasis yourself or you are a beginner in ... Acne conglobata is a rare severe form of nodulocystic acne. It presents with groups of multiple comedones and inflammatory papules, pustules, and nodules involving the trunk, limbs, and buttocks. Interconnecting abscesses and draining sinuses become secondarily infected causing pain and malodour. Healing is slow, leaving unsightly hypertrophic ... Tinea corporis is spread by the shedding of fungal spores from infected skin. Transmission is facilitated by a warm, moist environment and the sharing of fomites including bedding, towels, and clothing. Dermatophyte infection elsewhere on the skin, such as tinea pedis, can also be transferred. The incubation period is 1–3 weeks.Lentigo maligna is a precursor to lentigo maligna melanoma, a potentially serious form of skin cancer. Lentigo maligna is also known as Hutchinson melanotic freckle. Lentigo maligna is an early form of melanoma in which the malignant cells are confined to the tissue of origin, the epidermis, hence it is often reported as ‘ in situ ’ melanoma.Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss. Granuloma annulare may be a delayed hypersensitivity reaction to a component of the dermis or a reaction pattern to numerous triggers. Reported triggering events have included many skin infections and infestations, and types of skin trauma. Inflammation is mediated by tumour necrosis factor alpha ( TNF α). The reason this occurs is unknown. Anogenital warts are an infection caused by specific human papillomavirus types, most commonly HPV types 6 and 11. Warts will usually appear three to six months after infection but they may appear months or even years later. Anogenital warts are usually a sexually transmitted infection (STI).Principles of treatment. Despite recent advances in our understanding of the mechanism of how psoriasis develops, psoriasis may be difficult to treat; there is currently no cure and …Adults. Assess risk factors and comorbid disease of psoriasis at presentation and as indicated thereafter. Cardiovascular risk factors, and management of these (eg, smoking cessation ) Measure blood pressure, lipid studies and fasting glucose at least annually. Risk of venous thromboembolism and its management [1]. Introduction. If you don't find what you are looking for on this page, try DermNet's Glossary of Dermatology Terms or Dermatological diagnoses often have more than one name. . DermNet refers to various resources when naming conditions, including the World Health Organisation (WHO)'s International Classification of Diseases (see ICD11 coding tool), and the Systematized Nomenclature of Medicine ... Lichen planus is a chronic inflammatory condition affecting the skin and mucosal surfaces. Learn about its symptoms, causes, diagnosis, treatment, and complications with images … Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss. Aphthous ulceration is classified into three types. Recurrent minor aphthous ulcer (80%). This is less than 5 mm in diameter and heals within 1–2 weeks. Major aphthous ulcer, which is large (often more than 10 mm) and takes weeks or months to heal and leaves a scar. Herpetiform ulcers, which are multiple pinpoint ulcers that heal within a month. Dermatoporosis is a term used to describe chronic cutaneous insufficiency and fragility associated with both intrinsic and extrinsic ageing. The features of dermatoporosis include: Skin fragility and atrophy. Senile purpura. Stellate pseudoscars (star-shaped white patches) Non-healing atrophic ulcers. Scarlet fever usually starts with a sudden fever associated with sore throat, swollen neck glands, headache, nausea, vomiting, loss of appetite, swollen and red strawberry tongue, abdominal pain, body aches, and malaise. The characteristic rash appears 12–48 hours after the start of the fever. The rash usually starts below the ears, …DermNet NZ Editor in Chief: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Gus Mitchell/Maria McGivern. October 2018. Table of contents What are brown spots and freckles? Brown spots and freckles on sun-exposed skin are ephelides (the plural of ephelis) and lentigines (the plural of lentigo). The difference ...Chronic paronychia is a gradual process. It may start in one nail fold, particularly the proximal nail fold, but often spreads laterally and to several other fingers. Each affected nail fold is swollen and lifted off the nail plate. This allows the entry of organisms and irritants. The affected skin may be red and tender from time to time, and ...Keratosis pilaris is a very common, dry skin condition caused by keratin accumulation in the hair follicles. The Latin term keratosis means ‘ scaly skin’, and pilaris means ‘hair’. Keratosis pilaris usually starts in …Aphthous ulceration is classified into three types. Recurrent minor aphthous ulcer (80%). This is less than 5 mm in diameter and heals within 1–2 weeks. Major aphthous ulcer, which is large (often more than 10 mm) and takes weeks or months to heal and leaves a scar. Herpetiform ulcers, which are multiple pinpoint ulcers that heal within a month.Parkes-Weber syndrome refers to the association of a capillary vascular malformation with an arteriovenous malformation. The birthmark tends to be quite large. It is often faint pink, but may also be bright red in colour. The affected limb is warmer and longer than the other side, though of normal shape.Patch testing is undertaken for the investigation and confirmation of substances that produce allergic contact dermatitis. It involves applying appropriately diluted allergens to the skin, usually on the back for convenience, for 48 hours. The patch tests are then read at 96 hours as reactions usually take 48–96 hours to develop.Moisturisers are products used to add moisture to the skin. Emollients are products used to soften and smooth skin (eg, lanolin, glycerol stearate). Although the terms emollient and moisturiser are often used synonymously, emollients can also be described as a specific ingredient of moisturisers. There are often a number of available moisturisers.In New Zealand, a special authority application is required for a subsidy of biologic treatments [20,22]. A dermatologist is required to apply on behalf of the patient. The eligibility criteria include having 'whole body' severe chronic plaque psoriasis with a PASI score of > 10 (> 15 for infliximab) or severe chronic plaque psoriasis of the face, palm or …Moisturisers are products used to add moisture to the skin. Emollients are products used to soften and smooth skin (eg, lanolin, glycerol stearate). Although the terms emollient and moisturiser are often used synonymously, emollients can also be described as a specific ingredient of moisturisers. There are often a number of available moisturisers.Hyperhidrosis is the name given to excessive and uncontrollable sweating. Sweat is a weak salt solution produced by the eccrine sweat glands. These are distributed over the entire body but are most numerous on the palms and soles (with about 700 glands per square centimetre).Henoch–Schönlein purpura (HSP) is a form of leukocytoclastic or small-vessel vasculitis, most often observed in children. It is sometimes called anaphylactoid purpura. HSP results from inflammation of the small blood vessels in the skin and various other tissues within the body. HSP generally affects children, but it may also occur in adult ... Cutaneous features of periorificial dermatitis include: An acneiform eruption. Clusters of skin-coloured to red papules, vesicles, and pustules. Usually less than 2mm each; may coalesce into larger lesions. Erythematous base with a sharp border. Surrounding skin is often dry. Scaly and flaky skin surface. Principles of treatment. Despite recent advances in our understanding of the mechanism of how psoriasis develops, psoriasis may be difficult to treat; there is currently no cure and …DermNet won the 2017 New Zealand Ministry of Health Clinician's Challenge Award for the development of a skin disease image recognition tool. [9] [10] In 2017, Oakley won the … Acne conglobata is a rare severe form of nodulocystic acne. It presents with groups of multiple comedones and inflammatory papules, pustules, and nodules involving the trunk, limbs, and buttocks. Interconnecting abscesses and draining sinuses become secondarily infected causing pain and malodour. Healing is slow, leaving unsightly hypertrophic ... Infection of internal organs, including the gastrointestinal tract, lungs, and brain ( encephalitis) Herpes zoster is infectious to people who have not previously had chickenpox. Herpes zoster in the early months of pregnancy can harm the fetus, but luckily this is rare. Shingles in late pregnancy can cause chickenpox in the fetus or newborn. Granuloma annulare may be a delayed hypersensitivity reaction to a component of the dermis or a reaction pattern to numerous triggers. Reported triggering events have included many skin infections and infestations, and types of skin trauma. Inflammation is mediated by tumour necrosis factor alpha ( TNF α). The reason this occurs is unknown. 301 Moved Permanently. nginx/1.10.3Skin conditions caused or aggravated by infection by malassezia include: Pityriasis versicolor – most often due to M. globosa, M. sympodialis and M. furfur. Malassezia folliculitis due to the yeast growing in the hair follicles where they produce inflammation. Steroid acne. Seborrhoeic dermatitis, dandruff, sebopsoriasis and facial or scalp ...Mohs micrographic surgery, or Mohs surgery, is a precise surgical technique in which the complete excision of skin cancer is checked by microscopic margin control. It offers the highest cure rates while maximizing preservation of healthy tissue. The principles behind it were developed by Dr Frederic Mohs in the 1930s.Itchy anus is a common complaint described as an intense itch in the perianal area between the buttocks. Perianal itch can be the result of an infestation, skin infection, inflammatory skin condition, and, rarely, a skin tumour. When there is no obvious cause for the itch it is called pruritus ani.Tofacitinib (Xeljanz, Xeljanz XR ®, US) is an oral small- molecule inhibitor of Janus kinase (JAK) 1 and 3 that is used to treat psoriatic arthritis, rheumatoid arthriti s, inflammatory bowel disease, and ankylosing spondylitis. JAK enzymes respond to extracellular growth factors, and cytokines which activate signal transduction and cell ...Folliculitis means an inflamed hair follicle due to any cause. The result is a tender red spot, often with a surface pustule. Folliculitis may be superficial or deep. It can affect anywhere there are hairs, including chest, back, buttocks, arms, and legs. Acne and its variants are also types of folliculitis.It feels soft and smooth and is easily moved under the skin with the fingers. It may have a rubbery or doughy consistency. Lipomas are most common on the shoulders, neck, trunk and arms, but they can occur anywhere on the body where fat tissue is present. Most lipomas are symptomless, but some are painful when applying pressure.Seborrhoeic keratosis is a harmless warty spot that appears during adult life as a common sign of skin ageing. Some people have hundreds of them. Seborrhoeic keratosis (American spelling - seborrheic keratosis) is also called SK, basal cell papilloma, senile wart, brown wart, wisdom wart, or barnacle. The descriptive term, benign keratosis, is ...Urticaria pigmentosa. Urticaria pigmentosa is a form of cutaneous mastocytosis in which there are brown macules and papules. Urticaria pigmentosa is mostly seen in infants and improves with age. It may also arise in adults when it tends to persist. Lesions may affect trunk and limbs, and less often scalp and face. Dermatoporosis is a term used to describe chronic cutaneous insufficiency and fragility associated with both intrinsic and extrinsic ageing. The features of dermatoporosis include: Skin fragility and atrophy. Senile purpura. Stellate pseudoscars (star-shaped white patches) Non-healing atrophic ulcers. Sun damage ( photoageing, actinic keratoses) Repeated prior episodes of sunburn. Fair skin, blue eyes and blond or red hair — note; BCC can also affect darker skin types. Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, sebaceous naevus) Inherited syndromes: BCC is a particular problem for families with basal cell naevus ...See full list on dermnetnz.org Scalp psoriasis is a skin condition characterised by red, thickened, well- demarcated patches or plaques with overlying silvery-white scales, affecting part or all of the scalp. It can be contained within the hairline, though frequently affects the back of the head, or extends onto the forehead ( facial psoriasis ), ears, or neck.Cutaneous features of periorificial dermatitis include: An acneiform eruption. Clusters of skin-coloured to red papules, vesicles, and pustules. Usually less than 2mm each; may coalesce into larger lesions. … Macular amyloidosis is generally pruritic, although the degree of pruritus varies from mild to severe. It can assume a subtle rippled or reticulated pattern, which resembles the ‘seafloor pattern’ seen in lichen amyloidosis. Macular amyloidosis may co-exist with lichen amyloidosis in up to 25% of affected patients [9]. Strictly apple, Rainbow gardens san antonio, Douglas airport charlotte, Clayton university georgia, Sigma aldrich company, Tiestos, Saars market, Little elm tx, Juicy j and, City of beaverton, Stern cardiovascular, American psychiatric nurses association, Wholesale central, Healing arts center

Keratosis pilaris is a very common, dry skin condition caused by keratin accumulation in the hair follicles. The Latin term keratosis means ‘ scaly skin’, and pilaris means ‘hair’. Keratosis pilaris usually starts in …. Diamante cabo

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Principles of treatment. Despite recent advances in our understanding of the mechanism of how psoriasis develops, psoriasis may be difficult to treat; there is currently no cure and …Tinea corporis is spread by the shedding of fungal spores from infected skin. Transmission is facilitated by a warm, moist environment and the sharing of fomites including bedding, towels, and clothing. Dermatophyte infection elsewhere on the skin, such as tinea pedis, can also be transferred. The incubation period is 1–3 weeks.Lichen planus is a chronic inflammatory condition affecting the skin and mucosal surfaces. Learn about its symptoms, causes, diagnosis, treatment, and complications with images …Chronic paronychia is a gradual process. It may start in one nail fold, particularly the proximal nail fold, but often spreads laterally and to several other fingers. Each affected nail fold is swollen and lifted off the nail plate. This allows the entry of organisms and irritants. The affected skin may be red and tender from time to time, and ...Methylisothiazolinone allergy is diagnosed from the clinical history and by performing patch tests to MI and MCI/MI mix. MI is tested 0.2% in aqueous solution. MCI/MI is tested as a 0.01% mix in aqueous solution. These are both included in the Australasian Standard Series. Only CMI/MI is available in the True Test Kit and one study in 2015 …Risankizumab is an interleukin IL-23 antagonist indicated for the treatment of moderate-to-severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy [1]. Risankizumab was approved by the US Food and Drug Administration (FDA) in April 2019, in Japan in March 2019, and by the European Union in March 2019.Rheumatoid arthritis initially affects the small joints, such as those in the hands, but in later stages can affect any joint. It presents as episodic flares of symmetrical synovitis (swelling, redness, pain of joints), morning stiffness, and enthesitis. Untreated, it progresses to irreversible joint destruction with loss of cartilage and bone. Introduction. Itch is defined by a desire to scratch. An acute or chronic itchy rash is most often due to dermatitis / eczema. Dermatitis can be primary, or secondary to scratching. Stages include: Acute dermatitis: red, oozy, swollen skin. Subacute dermatitis: red, dry skin. Chronic dermatitis: skin coloured or dark, dry, thickened skin with ... Keratosis pilaris is a very common, dry skin condition caused by keratin accumulation in the hair follicles. The Latin term keratosis means ‘ scaly skin’, and pilaris means ‘hair’. Keratosis pilaris usually starts in …Aphthous ulceration is classified into three types. Recurrent minor aphthous ulcer (80%). This is less than 5 mm in diameter and heals within 1–2 weeks. Major aphthous ulcer, which is large (often more than 10 mm) and takes weeks or months to heal and leaves a scar. Herpetiform ulcers, which are multiple pinpoint ulcers that heal within a month.Malassezia folliculitis, also known as pityrosporum folliculitis, is an infection of the pilosebaceous unit caused by lipophilic Malassezia yeasts particularly M. globosa, M. sympodialis and M. restricta. Malassezia yeast are normal inhabitants of the human skin surface and only cause disease under specific conditions.Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. Learn … A melanocytic naevus (American spelling ‘ nevus ’), or mole, is a common benign skin lesion due to a local proliferation of pigment cells ( melanocytes ). It is sometimes called a naevocytic naevus or just 'naevus' (but note that there are other types of naevi ). A brown or black melanocytic naevus contains the pigment melanin, so may also ... Cutaneous T-cell lymphoma can cause harmless swelling, known as reactive or dermopathic lymphadenopathy, or malignant growth in the lymph nodes. The blood count is normal in most patients with CTCL. An elevated white cell count is characteristic of Sézary syndrome and confirmed on flow cytometry.Adults. Assess risk factors and comorbid disease of psoriasis at presentation and as indicated thereafter. Cardiovascular risk factors, and management of these (eg, smoking cessation ) Measure blood pressure, lipid studies and fasting glucose at least annually. Risk of venous thromboembolism and its management [1]. Scabies is a transmissible skin disease caused by the ectoparasitic mite Sarcoptes scabiei var. hominis. This variant infests humans only; scabies cannot be caught or transferred to other animals. Scabies is a highly contagious infestation of the human epidermis. Scabies was described by Aristotle who likened the disease to lice of the flesh. Erythema multiforme is an immune-mediated, typically self-limiting, mucocutaneous condition characterised by ‘target’ lesions . Significant mucosal involvement distinguishes erythema multiforme major from multiforme minor. Episodes can be isolated, recurrent, or persistent. In most cases, erythema multiforme is precipitated by herpes ...Pityriasis rosea is a self-limiting rash that resolves in about 6–10 weeks. It is characterised by a large circular or oval "herald patch" on the chest, abdomen, or back, followed by … Photodynamic therapy (PDT) is a treatment used mainly for superficial types of skin cancer. PDT is effective in treating actinic keratoses, in situ squamous cell carcinoma (Bowen disease), and superficial basal cell carcinomas. It may also be used for treatment of small, thin, low-risk nodular basal cell carcinomas outside of the head and neck ... Author: Qiuyu Jin, Medical Student, University of Auckland, Auckland, New Zealand. DermNet NZ Editor in Chief: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Gus Mitchell/Maria McGivern. June 2019. DermNet NZ Update July 2021 Pityriasis rosea is a self-limiting rash, which resolves in about 6–10 weeks. It is characterised by a large circular or oval "herald patch", usually found on the chest, abdomen, or back. The herald patch is followed some time later, typically two weeks or so, by the development of smaller scaly oval red patches, resembling a Christmas tree ... Contact dermatitis (also called contact eczema) refers to a group of skin disorders in which the skin reaction is due to direct contact with the causative agent. The term dermatitis implies that the outside layers of skin are affected. It can be acute (a single episode) or chronic ( persistent ). Dermatitis is nearly always itchy.The mottled appearance of cutis marmorata is caused by superficial small blood vessels in the skin dilating and contracting at the same time. Dilation creates the red colour of the skin whilst contraction produces a pale appearance. This phenomenon is most pronounced when the skin is cooled. The reasons for the reaction are not fully understood.Metastatic calcinosis cutis occurs in the setting of abnormal calcium and phosphate metabolism and is often associated with hypercalcaemia and/or hyperphosphataemia. Conditions that can cause metastatic calcinosis cutis may include: Primary or secondary hyperparathyroidism. Paraneoplastic hypercalcaemia. Destructive bone disease, such …Introduction. If you don't find what you are looking for on this page, try DermNet's Glossary of Dermatology Terms or Dermatological diagnoses often have more than one name. DermNet refers to various resources when naming conditions, including the World Health Organisation (WHO)'s International Classification of Diseases (see ICD11 coding tool), …Photodynamic therapy (PDT) is a treatment used mainly for superficial types of skin cancer. PDT is effective in treating actinic keratoses, in situ squamous cell carcinoma (Bowen disease), and superficial basal cell carcinomas. It may also be used for treatment of small, thin, low-risk nodular basal cell carcinomas outside of the head and neck ...Tinea corporis is spread by the shedding of fungal spores from infected skin. Transmission is facilitated by a warm, moist environment and the sharing of fomites including bedding, towels, and clothing. Dermatophyte infection elsewhere on the skin, such as tinea pedis, can also be transferred. The incubation period is 1–3 weeks.DermNet does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.DermNet does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.Angioedema is caused by an increase in local capillary permeability and plasma extravasation, usually mediated by mast cells, histamine, or bradykinin release. Angioedema is most commonly histamine-mediated; mast cell and basophil stimulation results in histamine release. Angioedema with urticaria tends to suggest a histaminergic … Sun damage ( photoageing, actinic keratoses) Repeated prior episodes of sunburn. Fair skin, blue eyes and blond or red hair — note; BCC can also affect darker skin types. Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, sebaceous naevus) Inherited syndromes: BCC is a particular problem for families with basal cell naevus ... Methylisothiazolinone allergy is diagnosed from the clinical history and by performing patch tests to MI and MCI/MI mix. MI is tested 0.2% in aqueous solution. MCI/MI is tested as a 0.01% mix in aqueous solution. These are both included in the Australasian Standard Series. Only CMI/MI is available in the True Test Kit and one study in 2015 …COVID-19 (coronavirus disease 2019) is a contagious viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 was first reported in December 2019 after a cluster of pneumonia cases in. Wuhan, China. It subsequently spread worldwide, prompting the World Health Organization (WHO) to declare a global pandemic ...Ramsay Hunt syndrome is a rare peripheral facial neuropathy. It is a type of shingles due to reactivation of the varicella zoster virus (VZV) in the geniculate ganglion of cranial nerve VII, which supplies the facial nerve. Ramsay Hunt syndrome is characterised by unilateral facial weakness and painful blisters — either in the ear canal on ...DermNet NZ is a comprehensive online resource for skin health information. Learn about psoriasis, a chronic inflammatory skin condition with red and scaly plaques, its types, causes, diagnosis and treatment options.Dermatosis is a generic term for a disease of the skin. When examining the skin, a dermatologist assesses distribution, morphology and arrangement of skin lesions: their …DermNet NZ Editor in Chief: Adjunct A/Prof Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Gus Mitchell/Maria McGivern. October 2018. Table of contents What are brown spots and freckles? Brown spots and freckles on sun-exposed skin are ephelides (the plural of ephelis) and lentigines (the plural of lentigo). The difference ...Metastatic calcinosis cutis occurs in the setting of abnormal calcium and phosphate metabolism and is often associated with hypercalcaemia and/or hyperphosphataemia. Conditions that can cause metastatic calcinosis cutis may include: Primary or secondary hyperparathyroidism. Paraneoplastic hypercalcaemia. Destructive bone disease, such … Tender or asymptomatic. Actinic keratoses are very common on sites repeatedly exposed to the sun, especially the backs of the hands and the face, most often affecting the ears, nose, cheeks, upper lip, vermilion of the lower lip, temples, forehead, and balding scalp. In severely chronically sun-damaged individuals, they may also be found on the ... DermNet NZ is a comprehensive online resource for skin diseases and conditions. Learn about acne, a common chronic disorder affecting the hair follicle and sebaceous gland, its causes, features, treatment options, and …What are the features of benign skin lesions? The features in common for benign skin lesions include: Symmetry in shape, colour and structure. Stable or slowly evolving. … Tender or asymptomatic. Actinic keratoses are very common on sites repeatedly exposed to the sun, especially the backs of the hands and the face, most often affecting the ears, nose, cheeks, upper lip, vermilion of the lower lip, temples, forehead, and balding scalp. In severely chronically sun-damaged individuals, they may also be found on the ... Cutaneous features of periorificial dermatitis include: An acneiform eruption. Clusters of skin-coloured to red papules, vesicles, and pustules. Usually less than 2mm each; may coalesce into larger lesions. Erythematous base with a sharp border. Surrounding skin is often dry. Scaly and flaky skin surface. A target lesion is a round skin lesion with three concentric colour zones: A bright red outermost ring. Target lesions typically occur in erythema multiforme. They can arise on any body site, including face, upper chest, back, arms, legs, hands, feet and mucous membranes (such as the lips). A target lesion is also called a bulls-eye lesion or a ...It affects the superficial layers of the epidermis and is typically caused by Staphylococcus aureus and Streptococcus pyogenes (Group A beta – haemolytic streptococci (GABHS)). It can be classified into non- bullous (also known as ‘school sores’) and bullous impetigo. Ecthyma is a deep form of impetigo causing deeper erosions of the skin ...Scarlet fever usually starts with a sudden fever associated with sore throat, swollen neck glands, headache, nausea, vomiting, loss of appetite, swollen and red strawberry tongue, abdominal pain, body aches, and malaise. The characteristic rash appears 12–48 hours after the start of the fever. The rash usually starts below the ears, …DermNet NZ is a comprehensive online resource for skin diseases and conditions. Learn about acne, a common chronic disorder affecting the hair follicle and sebaceous gland, its causes, features, treatment options, and …Tofacitinib (Xeljanz, Xeljanz XR ®, US) is an oral small- molecule inhibitor of Janus kinase (JAK) 1 and 3 that is used to treat psoriatic arthritis, rheumatoid arthriti s, inflammatory bowel disease, and ankylosing spondylitis. JAK enzymes respond to extracellular growth factors, and cytokines which activate signal transduction and cell ...Darier disease is an autosomal dominant genetic disorder classified as a hereditary acantholytic dermatosis. Darier disease typically presents with scaly crusted papules in a seborrhoeic distribution and in skin folds. Also …Dermatosis is a generic term for a disease of the skin. When examining the skin, a dermatologist assesses distribution, morphology and arrangement of skin lesions: their …Tinea versicolor is more accurately called pityriasis versicolor. This is a common yeast infection on the trunk. Tinea incognito refers to a tinea infection in which the clinical appearance has changed because of inappropriate treatment. Tinea nigra is a mould infection (not a dermatophyte). It affects the palms or soles, which appear brown (on ...Trachyonychia is characterised by brittle nails that show diffuse longitudinal ridging and can be accompanied by pitting, loss of lustre, or a roughened nail plate. Trachyonychia, also known as ‘rough nails’ or ‘sandpaper nails’, can involve any number of nails. Twenty-nail dystrophy refers to trachyonychia that affects all 20 nails.Cutaneous features of periorificial dermatitis include: An acneiform eruption. Clusters of skin-coloured to red papules, vesicles, and pustules. Usually less than 2mm each; may coalesce into larger lesions. …Sebaceous hyperplasia is the term used for enlarged sebaceous glands seen on the forehead or cheeks of the middle-aged and older people. Sebaceous hyperplasia appears as small yellow bumps up to 3 mm in diameter. Close inspection reveals a central hair follicle surrounded by yellowish lobules. There are often prominent blood vessels, best seen ...Erythromelalgia is characterised by intense burning pain, erythema (marked redness), and increased skin temperature, primarily of the feet and hands. It is classified into primary and secondary erythromelalgia. Erythromelalgia is also known as erythermalgia. Primary erythromelalgia with positive family history is known as Weir-Mitchell disease.DermNet is a not-for-profit, independent health publishing organisation with a mission to make authoritative information about the skin accessible to anyone in the world. We have information about almost every skin condition and have a library of over 20,000 dermatology images. All of our content is created or reviewed by a dermatologist and we ...Mohs micrographic surgery, or Mohs surgery, is a precise surgical technique in which the complete excision of skin cancer is checked by microscopic margin control. It offers the highest cure rates while maximizing preservation of healthy tissue. The principles behind it were developed by Dr Frederic Mohs in the 1930s.Melanoma of the nail unit is usually a variant of acral lentiginous melanoma, a malignant melanoma arising from the palms of the hands and soles of the feet. Other rare forms of melanoma that may arise in the nail unit are nodular melanoma or desmoplastic melanoma. Melanoma of the nail unit most often affects the great toe and thumbnail ...DermNet does not provide an online consultation service. If you have any concerns with your skin or its treatment, see a dermatologist for advice.Tofacitinib (Xeljanz, Xeljanz XR ®, US) is an oral small- molecule inhibitor of Janus kinase (JAK) 1 and 3 that is used to treat psoriatic arthritis, rheumatoid arthriti s, inflammatory bowel disease, and ankylosing spondylitis. JAK enzymes respond to extracellular growth factors, and cytokines which activate signal transduction and cell ...Skin conditions caused or aggravated by infection by malassezia include: Pityriasis versicolor – most often due to M. globosa, M. sympodialis and M. furfur. Malassezia folliculitis due to the yeast growing in the hair follicles where they produce inflammation. Steroid acne. Seborrhoeic dermatitis, dandruff, sebopsoriasis and facial or scalp ...Dermatitis herpetiformis (DH) is an inflammatoryimmunobullous disease of the skin and a cutaneousmanifestation of coeliac (celiac) disease, a gluten-sensitive enteropathy. The name herpetiformis is derived from the tendency for blisters to appear in clusters, resembling herpes simplex. However, DH is not due to viral infection.A PASI score is a tool used to measure the severity and extent of psoriasis. PASI is an acronym for Psoriasis Area and Severity Index. Completing a PASI score takes a few minutes and experience to calculate it accurately. Link to DermNet's patient-oriented PASI score tool (PO-PASI) if you have psoriasis yourself or you are a beginner in ... Alopecia areata is an autoimmune condition affecting hair follicles causing hair loss. It typically presents with discrete bald patches on the scalp but can cause hair loss from all hair-bearing areas on the body. Alopecia is a Latin term meaning hair loss, and areata refers to the patchy nature of the hair loss. Cold urticaria is a relatively uncommon form of chronic inducible urticaria. Urticarial weals develop after being exposed to cold, cold water, and cold objects. Acquired cold urticaria is now understood to be a completely different disorder from familial cold autoinflammatory syndrome (FCAS), previously known as hereditary cold urticaria. Sun damage ( photoageing, actinic keratoses) Repeated prior episodes of sunburn. Fair skin, blue eyes and blond or red hair — note; BCC can also affect darker skin types. Previous cutaneous injury, thermal burn, disease (eg cutaneous lupus, sebaceous naevus) Inherited syndromes: BCC is a particular problem for families with basal cell naevus ... DermNet is a worldwide clinical resource website about dermatology and skin conditions. Its co-founder and former editor-in-chief is dermatologist and Adjunct Associate Professor Amanda Oakley . [2] The website was launched in 1996 under the umbrella of the New Zealand Dermatological Society , and as of 2017, around 2 million people access the …Darier disease is an autosomal dominant genetic disorder classified as a hereditary acantholytic dermatosis. Darier disease typically presents with scaly crusted papules in a seborrhoeic distribution and in skin folds. Also …Anogenital warts are an infection caused by specific human papillomavirus types, most commonly HPV types 6 and 11. Warts will usually appear three to six months after infection but they may appear months or even years later. Anogenital warts are usually a sexually transmitted infection (STI).Dermatosis is a generic term for a disease of the skin. When examining the skin, a dermatologist assesses distribution, morphology and arrangement of skin lesions: their …Adults. Assess risk factors and comorbid disease of psoriasis at presentation and as indicated thereafter. Cardiovascular risk factors, and management of these (eg, smoking cessation ) Measure blood pressure, lipid studies and fasting glucose at least annually. Risk of venous thromboembolism and its management [1]. Guttate psoriasis is a clinical diagnosis, aided by dermoscopy, which can be confirmed on skin biopsy. Examination and investigations should include a search for streptococcal infection. Tests may include: Swabs for bacteriology. Blood tests — Anti-streptolysin O titre (ASOT), anti-DNase B titre. Malassezia folliculitis, also known as pityrosporum folliculitis, is an infection of the pilosebaceous unit caused by lipophilic Malassezia yeasts particularly M. globosa, M. sympodialis and M. restricta. Malassezia yeast are normal inhabitants of the human skin surface and only cause disease under specific conditions.Adults. Assess risk factors and comorbid disease of psoriasis at presentation and as indicated thereafter. Cardiovascular risk factors, and management of these (eg, smoking cessation ) Measure blood pressure, lipid studies and fasting glucose at least annually. Risk of venous thromboembolism and its management [1]. The term atypical naevus is sometimes used to mean any funny-looking mole, and sometimes to mean a melanocytic lesion that is suspected of being a melanoma (a cancerous mole). One definition of an atypical naevus is a mole with at least 3 of the following features. Size > 5 mm diameter. Ill-defined or blurred borders. . 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